They should make a video game where the controller is an actual guitar somehow, and you have to learn how to play it to control some kind of.. I dunno, Mario or GTA quest or whatever's your fancy.
Once upon a slime I had an in-depth conversation with someone about the possiblity of a guitar keyboard, where each fret would be a key and you could type obscure messages to people whilst playing songs. Melodies would be meaningful, classic novels could be translated into guitar parts, a delicate hanging spiderweb of revelation would dangle precariously above us all.
Then they posted a picture of that keytar thing. The world just wasn't ready.